![]() ![]() Unfer V, Carlomagno G, Dante G, et al.Myo-inositol may prevent gestational diabetes in PCOS women. D’Anna R, Di Benedetto V, Rizzo P, et al.Oral magnesium successfully relieves premenstrual mood changes. Facchinetti F, Borella P, Sances G, et al.L-theanine, a natural constituent in tea, and its effect on mental state. Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission. Theanine, an ingredient of green tea, inhibits glutamine transport in neurons and astroglia in rat brain. Pharmacological characterization of GABA receptors in tuarine-fed mice. L’Amoreaux WJ, Marsillo A, El Idrissi A, et al.Efects of increased adrenomedullary activity and taurine in young patient with borderline hypertension. Taurine increases mitochondrial buffering of calcium: role in neuroprotection. Central nervous system-activating drugs influencing hypothalamic-pituitary-adrenal axis function. Locatelli V, Bresciani E, Tomiazzo L, et al.Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans. Abdou AM, Higashiguchi S, Horie K, et al.Inositol treatment of obsessive-compulsive disorder. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. Double-blind, controlled trial of inositol treatment of depression. Myo-inositol content of common foods: development of a high mho-inositol diet. ![]() Based upon validated scoring procedures, double-blind, controlled, random-order crossover clinical trials using up to 18 g of myo-inositol per day for a month have demonstrated effectiveness with minimal to no side effects.* Inositol is a precursor for the second-messenger phosphatidyl-inositol system, which affects mood status differently than precursors for neurotransmitters. In contrast to low plasma concentration, the peripheral nerves have an extraordinarily high concentration of myo-inositol. Of the nearly 100% of ingested myo-inositol that is absorbed in the gastrointestinal tract, more than half becomes lipid bound. Fruits, beans, grains, and nuts contain some inositol however, an 1800-2500–calorie daily diet has been shown to provide only 225-1500 mg of myo-inositol. Inositol Present as the distinct isomer myo-inositol, inositol is a six-carbon cyclic polyalcohol that occurs naturally in all living cells. We also believe that optimal neurologic function is an important part in addressing these issues. These issues need to be addressed through calming & coping techniques such as Yoga, meditation, prayer, counseling, rest, etc. We strongly recommend a comprehensive, multi-pronged approach to these issues. Addressing these issues is of utmost priority! We find that many of our patients suffer from one or more of these issues. Stress, anxiety, sleep problems, ADHD, inability to focus, and countless other neurologic and psychological issues are extremely common today. ![]()
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